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KMID : 0191120220370080067
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Journal of Korean Medical Science
2022 Volume.37 No. 8 p.67 ~ p.67
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Kinetics of Neutralizing Antibody Responses Against SARS-CoV-2 Delta Variant in Patients Infected at the Beginning of the Pandemic
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Choe Pyoeng-Gyun
Kim Yu-Ri
Chang Eui-Jin
Kang Chang-Kyung
Kim Nam-Joong
Cho Nam-Hyuk
Park Wan-Beom
Oh Myoung-Don
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Abstract
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We investigated the kinetics of the neutralizing antibody responses to the severe acute respiratory syndrome-coronavirus-2 delta variant over the course of 1 year in 16 patients infected at the beginning of the pandemic. In patients with severe disease, neutralizing responses to the delta variant were detectable, albeit at lower levels than responses to the wild type. Neutralizing responses to the delta variant were undetectable, however, in asymptomatic persons. This finding implies that the vaccination strategy for persons with past natural infection should depend on the severity of the previous infection.
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KEYWORD
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COVID-19, SARS-CoV-2, Delta Variant, FRNT
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